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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4KB
All Species:
23.64
Human Site:
Y175
Identified Species:
47.27
UniProt:
Q9UBF8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBF8
NP_002642.1
816
91379
Y175
R
N
E
D
V
D
F
Y
L
P
Q
L
L
N
M
Chimpanzee
Pan troglodytes
XP_001171600
816
91257
Y175
R
N
E
D
V
D
F
Y
L
P
Q
L
L
N
M
Rhesus Macaque
Macaca mulatta
XP_001106422
828
92728
Y187
R
N
E
D
V
D
F
Y
L
P
Q
L
L
N
M
Dog
Lupus familis
XP_540314
945
105487
Y304
R
N
E
D
V
D
F
Y
L
P
Q
L
L
N
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKC8
816
91497
Y175
R
N
E
D
V
D
F
Y
L
P
Q
L
L
N
M
Rat
Rattus norvegicus
O08561
816
91637
Y175
R
N
E
D
V
D
F
Y
L
P
Q
L
L
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423394
743
82507
F148
R
L
F
E
S
K
L
F
D
I
S
M
A
I
S
Frog
Xenopus laevis
Q6GN16
804
90437
I163
E
P
G
V
Q
A
Y
I
G
N
R
L
F
C
F
Zebra Danio
Brachydanio rerio
Q49GP3
835
94040
F194
F
R
N
E
D
V
D
F
Y
L
P
Q
L
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524822
1674
181956
Y992
W
L
L
E
A
Y
N
Y
Q
V
D
S
L
G
N
Honey Bee
Apis mellifera
XP_391922
1078
119863
R408
L
Y
P
Y
L
V
H
R
C
R
Q
S
A
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39104
1066
119905
K247
L
I
D
P
I
K
T
K
E
D
A
S
F
R
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
84.2
N.A.
98.5
97.6
N.A.
N.A.
78.6
85.2
74.9
N.A.
25.7
42.1
N.A.
N.A.
Protein Similarity:
100
99.2
98.3
84.9
N.A.
99.1
98.6
N.A.
N.A.
83.4
90
82.7
N.A.
36.2
55.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
6.6
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
20
20
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
0
0
0
9
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% C
% Asp:
0
0
9
50
9
50
9
0
9
9
9
0
0
9
0
% D
% Glu:
9
0
50
25
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
9
0
9
0
0
0
50
17
0
0
0
0
17
0
17
% F
% Gly:
0
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
9
0
9
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
17
0
9
0
0
0
0
0
0
9
% K
% Leu:
17
17
9
0
9
0
9
0
50
9
0
59
67
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
50
% M
% Asn:
0
50
9
0
0
0
9
0
0
9
0
0
0
50
17
% N
% Pro:
0
9
9
9
0
0
0
0
0
50
9
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
0
59
9
0
0
0
% Q
% Arg:
59
9
0
0
0
0
0
9
0
9
9
0
0
9
0
% R
% Ser:
0
0
0
0
9
0
0
0
0
0
9
25
0
0
9
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
50
17
0
0
0
9
0
0
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
0
9
9
59
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _